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Staff picks: Our predictions for every Top 25 game include Big 12, SEC clashes

November 6, 2025
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Staff picks: Our predictions for every Top 25 game include Big 12, SEC clashes
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The Week 11 slate in college football features key contests in all the power conferences, which should give our panel of expert prognosticators a lot to consider.

The headliner is in the Big 12, a top-10 clash between No. 8 Brigham Young and No. 9 Texas Tech. There’s also a rather important ranked pairing in the Big Ten, as No. 6 Oregon visits No. 24 Iowa with both teams at one loss in the league and still in the race for the conference title game.

Of course, the SEC gets in on the act as well. No. 3 Texas A&M hits the road to No. 17 Missouri, and No. 4 Alabama hosts LSU. In other contests involving playoff contenders, No. 10 Notre Dame hosts its annual showdown with Navy, and No. 23 Memphis takes on Tulane in a key Friday night tilt in the American.

Will our staff pickers have differing opinions on those contests, and does anybody sniff a possible upset elsewhere? Read on to find out, and have a look at our season standings to date if you’re curious.

College football picks for Week 11

This post appeared first on USA TODAY
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